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Volume 1

Methods and Applications of Statistics in Clinical Trials, Volume 1: Concepts, Principles, Trials, and Designs successfully upholds the goals of the Wiley Encyclopedia of Clinical Trials by combining both previously-published and newly developed contributions written by over 100 leading academics, researchers, and practitioners in a comprehensive, approachable format. The result is a succinct reference that unveils modern, cutting-edge approaches to acquiring and understanding data throughout the various stages of clinical trial design and analysis.

Volume 2

Featuring newly-written material as well as established literature from the Wiley Encyclopedia of Clinical Trials, this book provides a timely and authoritative review of techniques for planning clinical trials as well as the necessary inferential methods for analyzing collected data.

This comprehensive volume features established and newly-written literature on the key statistical principles and concepts for designing modern-day clinical trials, such as hazard ratio, flexible designs, confounding, covariates, missing data, and longitudinal data. Examples of ongoing, cutting-edge clinical trials from today's research such as early cancer & heart disease, mother to child human immunodeficiency virus transmission, women's health initiative dietary, and AIDS clinical trials are also explored.

Content:
Chapter 1 The Future of Man—Evolutionary Aspects (pages 1–22): Julian Huxley
Chapter 2 Agricultural Productivip in Relation to Population (pages 23–35): Colin Clark
Chapter 3 Sophisticated Diets and Man's Health (pages 36–56): J. F. Brock
Chapter 4 World Resources (pages 57–78):
Chapter 5 Control of Reproduction in Mammals (pages 79–90): Gregory Pincus
Chapter 6 The Sex—Ratio in Human Populations (pages 91–119): A. S. Parkes
Chapter 7 World Population (pages 120–131):
Chapter 8 Growth and Development of Social Groups (pages 120–131): Carleton S. Coon
Chapter 9 Man's Relationship to His Environment (pages 132–152): Artur Glikson
Chapter 10 Machines and Societies (pages 132–167): D. M. Mackay
Chapter 11 Sociological Aspects (pages 168–187):
Chapter 12 The Promise of Medical Science (pages 188–195): Albert Szent?Gyorgyi
Chapter 13 Future of Infectious and Malignant Diseases (pages 196–216): Hilary Koprowski
Chapter 14 Longeuity of Man and His Tissues (pages 217–229): Alex Comfort
Chapter 15 Health and Disease (pages 230–246):
Chapter 16 Genetic Progress by Voluntarily Conducted Germinal Choice (pages 247–262): Hermann J. Muller
Chapter 17 Biological Future of Man (pages 263–273): Joshua Lederberg
Chapter 18 Eugenics and Genetics (pages 274–298):
Chapter 19 Potentialities in the Control of Behaviour (pages 299–314): Hudson Hoagland
Chapter 20 Future of the Mind (pages 315–321): Brock Chisholm
Chapter 21 Future of the Mind (pages 322–336):
Chapter 22 Biological Possibilities for the Human Species in the Next Ten Thousand Years (pages 337–361): J. B. S. Haldane
Chapter 23 Ethical Considerations (pages 362–383):

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