DMCA. Copyrighted Work that you can Claim.
Base have 223 081 books.
Search: 


📙 MHC Protocols by James Robinson, Steven G. E. Marsh (auth.), Stephen H. Powis, Robert W. Vaughan (eds.) — free pdf


Many of the genes found in the human major histocompatibility complex (MHC:HLA region) are subject to extreme polymorphism. HLA polymorphism has been used extensively in solid organ and bone marrow transplantation to match donors and recipients. Many MHC genes also have significant disease association and play a pivotal role in the control of immune response. In MHC Protocols, leading experts detail readily reproducible methods for identifying these polymorphisms in the human MHC. Described in step-by-step detail to ensure robust and successful experimental results, these techniques provide DNA-based protocols for the study of polymorphism in HLA class I and II genes and in non-HLA HMC genes associated with human disease (TAP1, TAP2, C2, C4, and TNF-a). The authors also describe methods for accessing HLA sequence data from electronic databases designed to catalog HLA-region genes and their alleles. Each method is written by an investigator who has used the technique extensively and includes troubleshooting tips and notes on pitfalls to avoid.
Comprehensive and highly practical, MHC Protocols offers both experienced and novice investigators not only a state-of-the-art overview of this dramatically evolving area of immunology, but also a reliable guide to the identification of MHC gene polymorphisms.



About book:

About file:

  • File size: 2 126 824
  • Format: pdf


Security code:
Download button

Similar books results


Antigen Processing and Presentation Protocols
Antigen Processing and Presentation Protocols download pdf by Joyce C. Solheim

Well-recognized and innovative experimentalists detail their cutting-edge methods for studying the antigen processing and presentation. Drawing on expertise from biochemistry, cell biology, and immunology, they describe step-by-step methods designed to qu...

HPLC of Peptides and Proteins: Methods and Protocols
HPLC of Peptides and Proteins: Methods and Protocols free epub by Marie-Isabel Aguilar (auth.), Marie-Isabel Aguilar (eds.)

High performance liquid chromatography (HPLC) plays a critical role today in both our understanding of biological processes and in the development of peptide and protein-based pharmaceuticals. In HPLC of Peptides and Proteins: Methods and Protocols, leadi...

Antigen Processing and Presentation Protocols (Methods in Molecular Biology Vol 156)
Antigen Processing and Presentation Protocols (Methods in Molecular Biology Vol 156) free download by Solheim J.C.

Well-recognized and innovative experimentalists detail their cutting-edge methods for studying the antigen processing and presentation. Drawing on expertise from biochemistry, cell biology, and immunology, they describe step-by-step methods designed to qu...

Protocols For High Efficiency Wireless Networks
Protocols For High Efficiency Wireless Networks epub download by Andreadis A., Giambene G.

The book, Protocols for High-Efficiency Wireless Networks, focuses on the air interface of mobile networks at different layers according to the OSI Reference Model. The authors provide an overview of several wireless communication systems including GPRS, ...

Directed Evolution Library Creation. Methods and Protocols
Directed Evolution Library Creation. Methods and Protocols free pdf by Frances H. Arnold, George Georgiou

A comprehensive compendium of cutting-edge protocols for the generation of molecular diversity. Described in step-by-step detail to ensure experimental success, these protocols include readily reproducible methods for random mutagenesis of entire genes or...

Ovarian Cancer. Methods and Protocols
Ovarian Cancer. Methods and Protocols free pdf by John M. S. Bartlett

Over one hundred well-respected scientists comprehensively review every aspect of the biology underlying ovarian cancer and present a remarkably detailed collection of easy-to-follow methods for illuminating basic mechanisms underlying all forms of cancer...

Chromatin Protocols
Chromatin Protocols free epub by Peter B. Becker

Collection of protocols is designed to analyze the relationship between chromatin structure and function, and to elucidate molecular mechanisms that control vital cellular functions such as transcription, replication, recombination, and DNA repair. Method...

Phospholipid Signaling Protocols
Phospholipid Signaling Protocols free pdf by Ian Bird

This wide-ranging collection of state-of-the-art techniques for the assay of phospholipid and phospholipid-derived second messengers allows the identification and quantification of signal pathway activation. The assays described cover all the major phosph...

In Vitro Mutagenesis Protocols
In Vitro Mutagenesis Protocols free pdf by Priya Handa, Swapna Thanedar, Umesh Varshney (auth.), Jeff Braman (eds.)

Hands-on researchers with proven track records describe in stepwise fashion their advanced mutagenesis techniques. The contributors focus on improvements to conventional site-directed mutagenesis, including a chapter on chemical site-directed mutagenesis,...