DMCA. Copyrighted Work that you can Claim.
Base have 178 088 books.
Search: 


📙 Microcalorimetry of Macromolecules: The Physical Basis of Biological Structures by Peter L. Privalov(auth.) — epub download


Examining the physical basis of the structure of macromolecules?proteins, nucleic acids, and their complexes?using calorimetric techniques

Many scientists working in biology are unfamiliar with the basics of thermodynamics and its role in determining molecular structures. Yet measuring the heat of structural change a molecule undergoes under various conditions yields information on the energies involved and, thus, on the physical bases of the considered structures. Microcalorimetry of Macromolecules offers protein scientists unique access to this important information.

Divided into thirteen chapters, the book introduces readers to the basics of thermodynamics as it applies to calorimetry, the evolution of the calorimetric technique, as well as how calorimetric techniques are used in the thermodynamic studies of macromolecules, detailing instruments for measuring the heat effects of various processes. Also provided is general information on the structure of biological macromolecules, proteins, and nucleic acids, focusing on the key thermodynamic problems relating to their structure. The book covers:

  • The use of supersensitive calorimetric instruments, including micro and nano-calorimeters for measuring the heat of isothermal reactions (Isothermal Titration Nano-Calorimeter), the heat capacities over a broad temperature range (Scanning Nano-Calorimeter), and pressure effects (Pressure Perturbation Nano-Calorimeter)
  • Two of the simplest but key structural elements: the ? and polyproline helices and their complexes, the ?-helical coiled-coil, and the pyroline coiled-coils
  • Complicated macromolecular formations, including small globular proteins, multidomain proteins and their complexes, and nucleic acids
  • Numerous examples of measuring the ground state of protein energetics, as well as changes seen when proteins interact

The book also reveals how intertwined structure and thermodynamics are in terms of a macromolecule's organization, mechanism of formation, the stabilization of its three-dimensional structure, and ultimately, its function. The first book to describe microcalorimetric technique in detail, enough for graduate students and research scientists to successfully plumb the structural mysteries of proteins and the double helix, Microcalorimetry of Macromolecules is an essential introduction to using a microcalorimeter in biological studies.

Content:
Chapter 1 Introduction (pages 1–3):
Chapter 2 Methodology (pages 5–32):
Chapter 3 Calorimetry (pages 33–67):
Chapter 4 Macromolecules (pages 69–94):
Chapter 5 The ??Helix and ??Helical Coiled?Coil (pages 95–125):
Chapter 6 Polyproline?II Coiled?Coils (pages 127–152):
Chapter 7 Globular Proteins (pages 153–191):
Chapter 8 Energetic Basis of Protein Structure (pages 193–224):
Chapter 9 Protein Folding (pages 225–247):
Chapter 10 Multidomain Proteins (pages 249–272):
Chapter 11 Macromolecular Complexes (pages 273–296):
Chapter 12 Protein–DNA Interaction (pages 297–351):
Chapter 13 Nucleic Acids (pages 353–385):

About book:

About file:

  • File size: 5 054 954
  • Format: pdf


Security code:
Download button

Similar books results


The Physical Basis of Biochemistry: Solutions Manual to the Second Edition
The Physical Basis of Biochemistry: Solutions Manual to the Second Edition free epub by Peter R. Bergethon, Kevin Hallock (auth.)

The Physical Basis of Biochemistry: Solutions Manual to the Second Edition offers solutions to the problem sets from the second edition of The Physical Basis of Biochemistry. The Physical Basis of Biochemistry is an introduction to the philosophy and prac...

Nonlinear Coherent Structures in Physics and Biology
Nonlinear Coherent Structures in Physics and Biology download pdf by J. C. Eilbeck, A. C. Scott (auth.), K. H. Spatschek, F. G. Mertens (eds.)

This volume contains the Proceedings of the NATO Advanced Research Workshop (ARW) and Emil-Warburg-Symposium (EWS) "Nonlinear Coherent Structures in Phy­ sics and Biology" held at the University of Bayreuth from June 1 -4, 1993. Director of the ARW was K....

The Physical Basis of Chemistry, Second Edition (Complementary Science)
The Physical Basis of Chemistry, Second Edition (Complementary Science) free epub by Warren S. Warren

If the text you're using for general chemistry seems to lack sufficient mathematics and physics in its presentation of classical mechanics, molecular structure, and statistics, this complementary science series title may be just what you're looking for. W...

Nutrient Dynamics and Biological Structure in Shallow Freshwater and Brackish Lakes
Nutrient Dynamics and Biological Structure in Shallow Freshwater and Brackish Lakes free pdf by Brian Moss (auth.), E. Mortensen, E. Jeppesen, M. Søndergaard, L. Kamp Nielsen (eds.)

The nutrient dynamics and biological structure of shallow non-stratified lakes differ markedly from that of deep and stratified lakes: for example, the return of nutrients lost through sedimentation is faster and the potential importance of fish and subme...

The Physical Basis of Chemistry
The Physical Basis of Chemistry free download by Warren S. Warren (Auth.)

If the descriptive text youre using for teaching general chemistry seems to lack sufficient mathematics and physics to make the results of its presentation of classical mechanics, molecular structure, and statisticsunderstandable, youre not alone. Written...

Hydrogen bonding in biological structures
Hydrogen bonding in biological structures download pdf by George A Jeffrey; Wolfram Saenger

Hydrogen bonds are weak attractions, with a binding strength less than one-tenth that of a normal covalent bond. However, hydrogen bonds are of extraordinary importance; without them all wooden structures would collapse, cement would crumble, oceans would...

Statistical Physics for Cosmic Structures
Statistical Physics for Cosmic Structures free download by Dr. Andrea Gabrielli, Dr. Francesco Sylos Labini, Professor Michael Joyce, Professor Luciano Pietronero (auth.)

The physics of scale-invariant and complex systems is a novel interdisciplinary field. Its ideas allow us to look at natural phenomena in a radically new and original way, eventually leading to unifying concepts independent of the detailed structure of th...

Seafloor Hydrothermal Systems: Physical, Chemical, Biological, and Geological Interactions
Seafloor Hydrothermal Systems: Physical, Chemical, Biological, and Geological Interactions free epub by

About The ProductPublished by the American Geophysical Union as part of the Geophysical Monograph Series. Hydrothennal circulation at mid-ocean ridges is one of the fundamental processes controlling the transfer of energy and matter from the interior of t...

Advances in Quantum Methods and Applications in Chemistry, Physics, and Biology
Advances in Quantum Methods and Applications in Chemistry, Physics, and Biology epub download by Brian Sutcliffe, R. Guy Woolley (auth.), Matti Hotokka, Erkki J. Brändas, Jean Maruani, Gerardo Delgado-Barrio (eds.)

Advances in Quantum Methods and Applications in Chemistry, Physics, and Biology includes peer-reviewed contributions based on carefully selected presentations given at the 17th International Workshop on Quantum Systems in Chemistry, Physics, and Biology. ...

Analog Circuits. World Class Designs
Analog Circuits. World Class Designs download pdf by Robert Pease

Newnes has worked with Robert Pease, a leader in the field of analog design to select the very best design-specific material that we have to offer. The Newnes portfolio has always been know for its practical no nonsense approach and our design content is ...

Analog Integrated Circuits for Communication
Analog Integrated Circuits for Communication free download by Donald O. Pederson, Kartikeya Mayaram

Analog Integrated Circuits for Communication: Principles, Simulation and Design, Second Edition covers the analysis and design of nonlinear analog integrated circuits that form the basis of present-day communication systems. Both bipolar and MOS transisto...

Analgesia
Analgesia free download by Christoph Stein, Christoph Stein

This volume attempts to summarize the current state of knowledge on mechanisms underlying the various effects of analgesics, their side effect profiles, and their indications and contraindications in clinical use. It also gives insights into current effor...

Analgesia, Anaesthesia and Pregnancy: A Practical Guide
Analgesia, Anaesthesia and Pregnancy: A Practical Guide download pdf by Steve Yentis, Anne May, Surbhi Malhotra

A thoroughly updated edition of this well-established practical guide to obstetric analgesia and anaesthesia originally published by W. B. Saunders. All aspects of obstetric medicine relevant to the anaesthetist are covered, from conception, throughout pr...

Anal Fistula - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
Anal Fistula - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References download pdf by Icon Health Publications

This is a 3-in-1 reference book. It gives a complete medical dictionary covering hundreds of terms and expressions relating to anal fistula. It also gives extensive lists of bibliographic citations. Finally, it provides information to users on how to upda...

  Anakin's Race for Freedom

Analogue Computing Methods
Analogue Computing Methods pdf free by D. Welbourne and P. Hammond (Auth.)

Analog and Hybrid Computing
Analog and Hybrid Computing free epub by D. E. Hyndman and N. Hiller (Auth.)

Anal Fistula: Principles and Management
Anal Fistula: Principles and Management free pdf by Richard L. Nelson M.D., F.A.C.S., Herand Abcarian M.D., F.A.C.S. (auth.), Herand Abcarian (eds.)

Anal Fistula: Principles and Management provides a comprehensive and state of the art review of major issues specific and related to the treatment of anal fistulas. An important section of the book covers the large number of alternative procedures which h...

Analogue Electronics for Higher Studies