DMCA. Copyrighted Work that you can Claim.
Base have 55 000 books.
Search: 


📙 Protein NMR Spectroscopy: Practical Techniques and Applications by — free download


Nuclear Magnetic Resonance (NMR) spectroscopy, a physical phenomenon based upon the magnetic properties of certain atomic nuclei, has found a wide range of applications in life sciences over recent decades. The dramatic advances in NMR techniques have led to corresponding advances in the ability of NMR to study structure, dynamics and interactions of biological macromolecules in solution under close to physiological conditions. This volume focuses on the use of NMR to study proteins.

NMR can be used to determine detailed three-dimensional structures of proteins in solution. Furthermore, it provides information about conformational or chemical exchange, internal mobility and dynamics at timescales varying from pcoseconds to seconds. It is the primary technique used to obtain information on intrinsically disordered (unfolded) proteins, since these proteins will not crystallize easily. NMR is also a very powerful method for the study of interactions of protein with other molecules, whether small molecules (including drugs), nuclear acids or other proteins.

This up-to-date volume covers NMR techiniques and their application to proteins, with a focus on practical details. This book will provide a newcomer to NMR with the practical guidance in order to carry out successful experiments with proteins and to analyze the resulting spectra. Those who are familiar with the chemical applications of NMR will also find is useful in understanding the special requirements of protien NMR.Content:
Chapter 1 Sample Preparation, Data Collection and Processing (pages 5–21): Frederick W. Muskett
Chapter 2 Isotope Labelling (pages 23–53): Mitsuhiro Takeda and Masatsune Kainosho
Chapter 3 Resonance Assignments (pages 55–82): Lu?Yun Lian and Igor L. Barsukov
Chapter 4 Measurement of Structural Restraints (pages 83–157): Geerten W. Vuister, Nico Tjandra, Yang Shen, Alex Grishaev and Stephan Grzesiek
Chapter 5 Calculation of Structures from NMR Restraints (pages 159–192): Peter Guntert
Chapter 6 Paramagnetic Tools in Protein NMR (pages 193–219): Peter H. J. Keizers and Marcellus Ubbink
Chapter 7 Structural and Dynamic Information on Ligand Binding (pages 221–267): Gordon Roberts
Chapter 8 Macromolecular Complexes (pages 269–317): Paul C. Driscoll
Chapter 9 Studying Partially Folded and Intrinsically Disordered Proteins Using NMR Residual Dipolar Couplings (pages 319–345): Malene Ringkjobing Jensen, Loic Salmon, Gabrielle Nodet, Phineus Markwick, Pau Bernado and Martin Blackledge

About book:

  • Author:
  • Year: 2011
  • Language: English
  • ISBN: 9780470721933,9781119972006

About file:

  • File size: 37 920 198
  • Format: pdf


Security code:
Download button

Similar books results


Protein-Ligand Interactions: Methods and Applications
Protein-Ligand Interactions: Methods and Applications download pdf by Edwin A. Lewis, Kenneth P. Murphy (auth.), G. Ulrich Nienhaus (eds.)

Molecular recognition and binding of ligands (atoms, ions, and molecules) by proteins with high sensitivity and selectivity is of central importance to essentially all biomolecular processes and of key importance for the basic and applied sciences. In Pro...

Annual Reports on NMR Spectroscopy, Volume 81
Annual Reports on NMR Spectroscopy, Volume 81 free epub by Graham A. Webb (Eds.)

Nuclear magnetic resonance (NMR) is an analytical tool used by chemists and physicists to study the structure and dynamics of molecules. In recent years, no other technique has gained such significance as NMR spectroscopy. It is used in all branches of sc...

NMR of Biomolecules: Towards Mechanistic Systems Biology
NMR of Biomolecules: Towards Mechanistic Systems Biology download pdf by

NMR is one of the most powerful methods for imaging of biomolecules. This book is the ultimate NMR guide for researchers in the biomedical community and gives not only background and practical tips but also a forward looking view on the future of NMR in s...

One and Two Dimensional NMR Spectroscopy
One and Two Dimensional NMR Spectroscopy epub download by Atta-ur- Rahman (Auth.)

The field of nuclear magnetic resonance spectroscopy has undergone explosive development during the last decade with the advent of new one- and two-dimensional techniques. The author has had extensive experience in the use of these techniques for the stru...

APM Best Practices: Realizing Application Performance Management
APM Best Practices: Realizing Application Performance Management download pdf by Michael J. Sydor (auth.)

The objective of APM Best Practices: Realizing Application Performance Management is to establish reliable application performance management (APM) practices—to demonstrate value, to do it quickly, and to adapt to the client circumstances. It's important ...

Practical MATLAB application for engineers
Practical MATLAB application for engineers download pdf by Misza Kalechman

Practical MATLAB application for engineers КНИГИ ; ПРОГРАММИНГ Название: Practical MATLAB application for engineers Автор: Kalechman M. Издательство: CRC Press Год: 2008 Страниц: 708 Формат: pdf Размер: 6,46 Мб Язык: английскийАннотацияPractical Matlab ...

Cavity Ring-Down Spectroscopy: Techniques and Applications
Cavity Ring-Down Spectroscopy: Techniques and Applications free pdf by

Cavity ring-down spectroscopy (CRDS) is a simple, highly sensitive direct absorption technique based on the rate of absorption of light circulating in an optical cavity. CRDS can be used to study atoms and molecules in the gas and condensed phase, and is ...

Inorganic Electrochemistry. Theory, Practice and Application
Inorganic Electrochemistry. Theory, Practice and Application free pdf by P. Zanello

Electrochemistry can be an elegant and essential support to synthetic inorganic chemistry. However, it is often perceived as a difficult technique. This book aims to introduce inorganic chemists to electrochemical investigations in as straightforward a wa...

Biomedical Applications of Biophysics
Biomedical Applications of Biophysics free pdf by Patrice Koehl (auth.), Thomas Jue (eds.)

HANDBOOK OF MODERN BIOPHYSICS Series Editor Thomas Jue, PhD Handbook of Modern Biophysics brings current biophysics topics into focus, so that biol-ogy, medical, engineering, mathematics, and physical-science students or researchers can learn fun¬damental...

Digital Image Processing: Concepts, Algorithms, and Scientific Applications
Digital Image Processing: Concepts, Algorithms, and Scientific Applications free pdf by Bernd Jähne

Since the first edition of Digital Image Processing was published in 1986 it has found its way to many desks and classrooms. The book offers an integral view of image processing from image acquisition to the extraction of the data of interest. The discuss...

Digital games and learning
Digital games and learning epub download by Sara de Freitas; Paul Maharg

Digital Heritage: Third International Conference, EuroMed 2010, Lemessos, Cyprus, November 8-13, 2010. Proceedings
Digital Heritage: Third International Conference, EuroMed 2010, Lemessos, Cyprus, November 8-13, 2010. Proceedings free epub by Hung-ming Cheng, Ya-ning Yen, Min-bin Chen, Wun-bin Yang (auth.), Marinos Ioannides, Dieter Fellner, Andreas Georgopoulos, Diofantos G. Hadjimitsis (eds.)

This volume comprises the proceedings of the Third International Euro-Mediterranean Conference (EuroMed 2010) on the historical island of Cyprus. The focal point of this conference was digital heritage, which all of us involved in the documentation of cul...

Digital Human Modeling: Second International Conference, ICDHM 2009, Held as Part of HCI International 2009, San Diego, CA, USA, July 19-24, 2009. Proceedings
Digital Human Modeling: Second International Conference, ICDHM 2009, Held as Part of HCI International 2009, San Diego, CA, USA, July 19-24, 2009. Proceedings epub download by Zhiqing Cheng, Kathleen Robinette (auth.), Vincent G. Duffy (eds.)

This book constitutes the refereed proceedings of the Second International Conference on Digital Human Modeling, ICDHM 2009, held in San Diego, CA, USA in July 2009.The 80 revised papers presented were carefully reviewed and selected from numerous submiss...

Digital Human Modeling: Third International Conference, ICDHM 2011, Held as Part of HCI International 2011, Orlando, FL, USA July 9-14, 2011. Proceedings
Digital Human Modeling: Third International Conference, ICDHM 2011, Held as Part of HCI International 2011, Orlando, FL, USA July 9-14, 2011. Proceedings free pdf by Wen-Ko Chiou, Bi-Hui Chen, Wei-Ying Chou (auth.), Vincent G. Duffy (eds.)

This book constitutes the refereed proceedings of the Third International Conference on Digital Human Modeling, ICDHM 2011, held in Orlando, FL, USA in July 2011. The 58 revised papers presented were carefully reviewed and selected from numerous submissio...

Digital Human Modeling: Trends in Human Algorithms
Digital Human Modeling: Trends in Human Algorithms download pdf by Kevin Warwick, Mark Gasson (auth.), Yang Cai (eds.)

The emerging information technologies have given rise to new human patterns in terms of both physiological and psychological interactions. Human Algorithms aim to model human forms, interactions, and dynamics in this new context. They are becoming increas...

Digital Image Processing Techniques
Digital Image Processing Techniques epub download by Michael P. Ekstrom (Auth.)

Digital Imaging Processing Techniques...

Digital Electronics
Digital Electronics download pdf by F. Dokter, J. Steinhauer (auth.)

Digital Hardware Design
Digital Hardware Design epub download by Ivor Catt, David Walton, Malcolm Davidson (auth.)

Digital Games in Language Learning and Teaching
Digital Games in Language Learning and Teaching free download by Hayo Reinders (eds.)

This edited volume explores how digital games have the potential to engage learners both within and outside the classroom and to encourage interaction in the target language. This is the first dedicated collection of papers to bring together state-of-the-...